In Prime Video's The Wheel of Time, a quasi-religious organization called the Children of the Light hate and hunt the Aes Sedai, an all-female magical order, for a few reasons that relate to the very core of the series' mythology. Also known as Whitecloaks, the Children of the Light are one of the many factions in The Wheel of Time series. A militaristic organization that seeks to route out Darkfriends, allies to the Dark One in the World of the Wheel, the Children of the Light hold no true authority in The Wheel of Time save for what their militaristic might grant them.
This is in stark contrast to the Aes Sedai. The Aes Sedai are granted authority in many regions of the world, both for their ability to protect people and for their connection to the True Source, which is derived from the Creator of the Wheel. This connection gives them the ability to channel the One Power, the magic system in The Wheel of Time, Despite this, though, many are fearful of the Aes Sedai precisely because of their power, as evidenced by the reaction to Moiraine's arrival in Emond's Field in The Wheel of Time episode 1.
While the citizens of Emond's Field may have expressed trepidation towards Aes Sedai, the Children of the Light are outright hostile to them because they believe that anyone who can wield the One Power is fighting for the Dark One himself. The Children of the Light see Aes Sedai as Darkfriends, some of the Dark One's primary allies in The Wheel of Time, and their fanaticism causes them to hate and hunt the Aes Sedai, both out of jealousy of their connection to the Creator of the titular Wheel of the Time and because of the fear of their power.
From the beginning of The Wheel of Time, it's clear that Moiraine Damodred (Rosamund Pike) is seeking to defeat the Dark One and so, too, are many of the other Aes Sedai. The only questionable faction within the Aes Sedai is the Red Ajah, who seek out men who can channel the One Power. Still, the Children of the Light are dangerous because of their fanaticism and zealous dedication to their cause, making these facts about the Aes Sedai a moot point in their eyes.
Still, religion is an interesting facet of The Wheel of Time, making it different from other fantasy shows in that it's not central to the conflict itself, but a means through which various groups hide their true intentions. With a link to the Creator (the One Power) so prevalent in society, the World of the Wheel doesn't need religion, but that doesn't stop the Children of the Light from operating with a pseudo-religious bent. It's this fanaticism that makes them so dangerous and their zeal in hunting the Aes Sedai, those who wish to stop the Dark One in The Wheel of Time, puts them in direct conflict with the goals of the series' protagonists.