Supernatural's Colt is a handy weapon to have around... most of the time. Here are the five things Sam and Dean Winchester's legendary gun can't vanquish. The trunk of Dean's Impala is stocked with tools perfect for killing monsters - angel blades, archangel blades, grenade launchers, Negan's baseball bat - but arguably the most famous Supernatural weapon is the Colt, a gun personally created by secret hunting legend, Samuel Colt.
Imbued with cosmic magicks, Supernatural's Colt requires a special kind of ammunition, but kills virtually anything with a single shot. Monsters that typically prove resistant to guns, holy water, blades, and other Winchester implements of destruction tremble at the mere sight of Sam and Dean's Colt. As Lucifer duly points out in Supernatural season 5, however, five beings are excluded. Annoyingly, Satan is the only Colt-proof villain Supernatural actually confirms across its entire 15-season run, leaving the remaining quartet a mystery...
If Supernatural's Colt can't kill Lucifer, one would assume that rule applies equally to fellow archangels Michael, Gabriel and Raphael - even if Sam and Dean never got around to testing that theory. And if Heaven's archangels would survive a bullet, it stands to reason that God, their father, would have natural Colt immunity too. Supernatural then throws a curveball by introducing God's sister, Amara. Anything God does his sister can do better, and that surely includes taking a bullet from the Colt, but counting Amara means Lucifer's "five things" must treat the archangels as one single entry, which leaves two slots empty.
Which Other Beings Can't Supernatural's Colt Kill?
Death feels like a strong contender to mark itself safe from Supernatural's Colt. Even among Horsemen, the infamous scythe-wielder plays by special rules, once claiming they and God were the universe's first and last beings. This puts Death on a higher level than even archangels, so it's very unlikely they'd be offed by a Colt bullet. Indeed, the only known weapon capable of ending Death is the Horseman's own scythe.
Supernatural season 13 debuts the Shadow, which rules over the angelic afterlife known as the Empty. Precious little is known about this entity aside from the fact it predates God and strikes fear even into the hearts of angels. The Shadow is never killed in Supernatural, but Billie claims it could survive the Jack-in-the-box bomb she designed to wipe out God. With such durability, firing a Colt bullet at the Shadow would probably be like shooting a lion with a NERF gun.
Why Lucifer Might've Meant A DIFFERENT Five Beings
The five beings Supernatural's Colt can't kill are already harder to unravel, but made even harder by conflicting interpretations of Lucifer's original line. In Supernatural season 5's "Abandon All Hope," the Devil says, "There's only five things in all of creation that that gun can't kill." While the quote was most likely intended to mean "the Colt can't kill five things," some argue Lucifer was specifically referring to created beings - i.e. excluding entities like God, Amara, Death and the Shadow. If so, who joins archangels on the list of Colt-proof monsters?
Whomever holds the Mark of Cain stands a decent hope of surviving the Colt. This curse was powerful enough to seal Amara, while also overwhelming the Knights of Hell. Leviathans were God's first monsters, and according to their tablet, only vulnerable to a big ol' blood-soaked bone. Supernatural doesn't confirm whether the Colt could've downed Dick, but Leviathans are among the sturdiest monsters Sam and Dean face.
Supernatural's Alpha Vampire once lied to Sam Winchester about being among these mythical "five beings," but while he got caught out, the mother of all monsters, Eve, makes a stronger claim for inclusion. The Winchesters could only defeat her with phoenix ash although, just like the Leviathans, the Colt wasn't in their possession when Eve was wreaking havoc, making the hypothesis impossible to test. The fifth and final entry could be the three non-Death Horsemen. Death was seemingly older than Famine, War and Pestilence (and, therefore, excluded from "creation"), but if the Colt can't kill one horseman, it probably can't kill any of the sinister siblings.