Here's Bill Compton's death in True Blood season 7 explained - and if there's any hope of resurrection. True Blood is based on The Southern Vampire Mysteries by author Charlaine Harris, which began in 2001. The show takes place in a world where vampires - having remained hidden away from the world - make themselves known and start to integrate into society. This is thanks to a blood substitute dubbed "Tru Blood," which means they don't need to feast on human blood to survive any longer.
True Blood cast Anna Paquin as Sookie, a psychic waitress who falls for brooding vampire Bill (Stephen Moyer). The show became something of a guilty pleasure hit when it debuted in 2008, and it wasn't afraid of a little bloodshed or gratuitous nudity. Fans of the series feel the quality really dipped in later seasons, with many also being disappointed by the season 7 finale, which brought the show itself to a close.
True Blood season 7 found Bill infected by Hepatitis V, which is fatal to vampires and induces "True Death." When given a chance to be cured of Hep-V, however, Bill decides he's ready to die. Sookie doesn't want to accept this decision and tries to talk him out of it, but during a conversion in the finale "Thank You" he not only doubles down - he wants Sookie to kill him with her Fae powers. This would make her human, and it's Bill's wish that she has a "normal" life without him.
Bill later gives his "progeny" Jessica (Deborah Ann Wolf) away in marriage to Hoyt, and Sookie later agrees to Bill's request. His final scene in True Blood sees Bill laying down in his old coffin from the Civil War era. He lays with a picture of his daughter Sarah, though Sookie ultimately decides to keep her powers as they're a "part of her." Despite really not wanting to go through with killing Bill, she respects his wish and together they drive a stake into his chest. He explodes in a geyser of blood, leaving a devasted Sookie screaming in his grave.
With Bill receiving "True Death" in True Blood's finale, that would seem to be that for the character. That said, he did "die" in season 5, where he exploded after drinking the blood of Lilith - the Progenitor of the vampire race - to receive her powers. Shortly after exploding, Bill reformed with some new powers, including resistance to being staked and telekinesis. He was later drained of her blood and abilities in season 6, but as the only known vampire to survive "True Death," it's not totally impossible for a True Blood reboot to contrive Lilith's blood bringing Bill back to (reluctant) life. It appears the upcoming HBO reboot with be taking place in a new continuity, so Stephen Moyer's Bill is unlikely to return.