Season 3 of The Boys should take a page from the playbook of Billy Butcher in the comics and use a dark tactic to even the playing field between themselves and The Seven: by secretly giving themselves superpowers. The events of season 2 made this possible, and with Homelander having several good personal reasons for going after them, The Boys could certainly use the upgrade.
Amazon Prime's The Boys series has made many changes from the comics that inspired it. One of the more notable ones involved Compound V, the mutagen that allowed humans to develop superpowers. In the show, Compound V was only given to children, as its effects on adults proved unpredictable. Despite this, the speedster A-Train was shown to use Compound V shots as a performance enhancer, similar to how a body-builder might use steroids. The main plotline of season 2 centered around Stormfront's efforts to develop an army of superhumans so she could build a new fascist government in the United States by creating an adult-safe formula of Compound V that she could give to "the right people."
In The Boys comic book, Compound V was safe for adults but also prohibitively expensive. A single high-quality dose of Compound V granting permanent superpowers cost $19 billion per injection, but less expensive strains of the drug were available and some of the children of those who had been exposed to pure Compound V (like Mother's Milk) developed superpowers naturally. In The Boys #4, as he was assembling the team, Billy Butcher gave Hughie Campbell a shot of the high-quality Compound V without telling him what it was before the drug was in his system. While Hughie was annoyed and gave Butcher the first of the many panic-driven rants that would define their relationship, he was thankful for the increased stamina and strength the drug gave him during The Boys' first fight with Teenage Kix two issues later. This was a marked contrast from the first two seasons of The Boys, where Butcher and his team depended on stealth and trickery to survive their encounters with various Supes, as there was no way they could survive a physical battle.
With none of The Boys or their allies having superpowers except for Kimiko and Starlight, the team on the show needs something to even the fight now that Homelander knows who they are. Worse yet, he has good reason to seek revenge after the team thwarted Stormfront's plan, leaving him without the loving family Homelander so desperately wanted. Thankfully, the story of The Boys season 2 has cleared a path for Butcher's dark plan from the comics to be used in season 3.
Thanks to Stormfront's secret lab, a strain of Compound V that was safe for adults was created and Vought International was ready to start giving it to soldiers and police officers before Stormfront's plan was exposed. More importantly, The Boys season 2 finale ended with Representative Victoria Neuman establishing a government organization charged with regulating superhumans and Butcher being offered a chance to form a team with official CIA backing. While Butcher never officially accepted the offer on camera, it's hard to imagine he wouldn't take the deal after trying to get CIA backing from Deputy CIA Director Susan Raynor at the start of season 2. Given all that, it seems likely that viewers will see The Boys with superpowers in season 3.