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Two colleagues at a revolutionary research lab design technology to improve and perfect romantic relationships. As their work progresses, their discoveries become more profound.
The film was in development as early as 2016, when Charlie Hunnam was in the lead male role. Ewan McGregor replaced Hunnam in 2017, joining the project with the rest of the supporting cast. Production started in May 2017. Zoe premiered at the Tribeca Film Festival in April 2018, where Amazon Studios acquired distribution rights.