Save Koch puts players in the shoes of a crime boss locked in a panic room after being informed that an anonymous head of a rival faction is looking to assassinate him in seven days. The titular Koch lives in a sci-fi noir inspired world full of anthropomorphized animals that are both complicated and interesting. The only information that the player is given about their situation is that there is a mole in their organization who is working for Koch's mysterious rival. From there players must make phone calls and send their underlings on missions to determine who the mole and mastermind are with each game randomizing those positions.

The gameplay of Save Koch is simple, but the game does very little to explain it to the player. Koch never leaves his desk, so players must use phone calls and the situation board in order to discover clues and new potential culprits. Any information that is acquired goes up on the board for players to analyze and draw conclusions. Understanding how all of these things work together is mostly trial and error, as even Save Koch's tutorial is little help.