To his credit, he is at least aware of the negative buzz and as far as I'm concerned that's a good thing. During his interview he actually said (concerning the brutally murdered Batman franchise):
"I'm not Joel Schumacher, and I'm not ... um ... who did the third Superman? I'm Brett, and all I know is what I know, what I can do and what I have to work with."
So he knows what's on the line and what can happen when things go terribly wrong.
Then there's a bit more hopeful news:
"I want to stay true to the franchise and true to the characters, but I think it's elevated ... I don't want to be pompous and say I'm going to take it to the next level. I think the script that Simon Kinberg and Zak Penn wrote gives me a tremendous amount of confidence."
Followed by a big red flag concerning injecting more humor into the upcoming sequel:
"Not jokes for the sake of jokes, jokes that come from character humor, that come from characters and that come from the situations."
In view of what I've read about the storyline, even bringing up humor scares me a bit.
Ratner also stated that Bryan Singer left X-Men 3 for Superman because he wasn't happy with the script. That's the first I've heard of that.