Fortunately, the twitterverse has delivered a set of stills from the LOST season premier with a humorous change in dialogue.Check out the photo mashup. WARNING: if you haven't seen the LOST Season 6 premiere these pictures definitely contain SPOILERS.
Maybe the mashup is onto something. The Avatar connection seems especially plausible considering the events occurring in the final seconds of the Lost premiere.
Got any other ideas for other LOST/Avatar mashups?