15Jennifer Aniston - Leprechaun
Breakout roles are hard to come by, and Jennifer Aniston's first film appearance was a bona fide flop. Leprechaun was a 1993 low-budget horror movie that spawned five unfortunate sequels, and it was also where the Friends star got her start.
Aniston has been unable to escape the shadow of her first film. She's constantly
asked about it, as it's still one of the most popular flops in which an A-list star has taken part. Virtually every press tour Aniston embarks on has at least one reporter who will mention Leprechaun, so she's gotten used to shrugging off the light mockery.
It's hard to completely regret the role, though. A year after this, Aniston was cast on Friends and the rest is history.