The Hotel Transylvania 4 cast contains a plethora of star names, with many bearing little resemblance in real life to their monstrous character counterparts. The fourth film in its respective franchise, Hotel Transylvania: Transformania, was released exclusively on Amazon Prime Video in January 2022 with several of Hotel Transylvania 4's main characters recast from the previous movies in the franchise. Hotel Transylvania 4 sees Dracula consider selling the eponymous hotel that forms the backdrop of the first three Hotel Transylvania movies before a mishap with a Monster Ray turns the vampiric patriarch and his cohort into humans.

His human nephew Johnny is also turned into a giant green dragon, leading the Dracula clan on a quest to South America in an effort to revert themselves to their original forms. The form-swapping fun does not end with Hotel Transylvania. The movie saw several of its core voice cast change hands, as both Adam Sandler and Kevin James relinquished their roles as Count Dracula and Frankenstein, respectively. This caused several major changes for the Hotel Transylvania 4 cast, with the new voice actors stepping in to keep the franchise alive.

Andy Samberg - Jonathan "Johnny" Loughran

Johnny is dealt something of a rough hand in the Hotel Transylvania universe as the only socially ostracized human within the Dracula family, as well as being Mavis' husband, Dracula's son-in-law, and Dennis' father. Hotel Transylvania: Transformania sees Johnny break the established order, however, as he turns monstrous while his immediate family all get a taste of the decidedly human life.

In the Hotel Transylvania 4 cast, Johnny is voiced by SNL alum and Baking It host, Andy Samberg, whose comedy film credits include Hot Rod, I Love You, Man, and the animated Cloudy With a Chance of Meatballs franchise. He also finished up a long-standing role in Brooklyn Nine-Nine in 2021 and lent his voice to Chip 'n Dale: Rescue Rangers in 2022 and Spider-Man: Across the Spider-Verse in 2023.

Selena Gomez - Mavis Dracula

Johnny's loyal wife Mavis has, just like her husband, seen many trials and tribulations after being determined to marry a human across the Hotel Transylvania franchise. Hotel Transylvania 4 grants Mavis and Johnny a chance to bring their own vision of the hotel to life, resulting in the Monster Ray mayhem that follows after Dracula cannot let go of his beloved building.

Mavis is voiced by American singer, actress, and producer Selena Gomez in the Hotel Transylvania 4 cast, whose recent film credits include Jim Jarmusch's critically acclaimed The Dead Don't Die. She most recently enjoyed her biggest role as one of the leads in the Hulu series Only Murders in the Building with Steve Martin and Martin Short, which earned her a Golden Globe nomination. She was the subject of her Apple TV documentary, Selena Gomez: My Mind & Me.

Kathryn Hahn - Ericka Van Helsing

Dracula's wife and the great-granddaughter of Abraham Van Helsing, Ericka often acts as the voice of reason against her husband's more petulant impulses. She is, however, unable to stop Count Dracula from breaking the Monster Ray, causing the entire Dracula clan to trek across the globe in search of a rare crystal to fix the transmogrifying machine.

In the Hotel Transylvania 4 cast, Ericka Van Helsing is played by comedy queen Kathryn Hahn. She has enjoyed several breakout roles in recent years. She took on the role of Raquel in Transparent before moving on to star as Agatha Harkness in the MCU Disney+ series WandaVision. She will return to that role in her own series in 2024. She also starred in the miniseries The Shrink Next Door in 2021 and Tiny Beautiful Things in 2022. She also had a major movie role in 2022 with her part in the Rian Johnson movie Glass Onion: A Knives Out Mystery.

Jim Gaffigan - Abraham Van Helsing

The legendary yet now retired monster hunter Abraham Van Helsing returns as the catalyst for Hotel Transylvania 4's body-morphing antics to take place. His Monster Ray is certainly a marvel to behold, although its idiosyncratic mechanisms ensure a long and arduous journey to South America for the franchise's protagonists. Abraham is played by stand-up comedian, actor, writer, and producer Jim Gaffigan in the Hotel Transylvania 4 cast, whose notable movie credits include The Love Guru and Super Troopers 2. In 2021, he joined the DCU with a role in Stargirl and also took on the role of Mr. Smee in 2023's Peter Pan & Wendy.

Steve Buscemi - Wayne

Steve Buscemi returns as the ever-popular werewolf Wayne in the Hotel Transylvania 4 cast, who finds himself in a human body bereft of Lycan blood following the ray's malfunction early in Hotel Transylvania 4. Wayne's voice actor needs little introduction, with Buscemi boasting an impressive body of work spanning the last 40 years. Buscemi is equally prevalent in the Hollywood animation industry, with his notable voice roles including Randall in the Monsters Inc. franchise, Francis in The Boss Baby, and Templeton in Charlotte's Web. Most recently, he also took on various roles in the comedy series Miracle Workers​​​​​.

Molly Shannon - Wanda

Wanda is the other half of Wayne and is, predictably, a less-than-ferocious werewolf across most of her appearances in the Hotel Transylvania franchise. However, unlike her husband, she is spared the ignominy of transforming into a human after refusing to drink from the ray-contaminated fountain that turns Wayne and several other monsters into ordinary people. Wanda's Hotel Transylvania 4 cast voice actor Molly Shannon boasts a vast and varied film and TV career, with the comedian most recently starring in HBO Max's seminal The White Lotus and the comedy series I Love That For You.

David Spade - Griffin

David Spade first saw success as a Saturday Night Live troupe member in the 1990s before going on to co-star in the films Tommy Boy and Black Sheep with the late comedy legend Chris Farley. More recently, Spade has starred alongside long-time friend Adam Sandler in numerous Netflix productions such as The Ridiculous 6, The Do-Over, and The Wrong Missy, and the first three Hotel Transylvania installments. Spade plays Griffin in the Hotel Transylvania 4 cast, an invisible man humorously derived from the works of H.G. Wells' original 1897 sci-fi novels.

Keegan-Michael Key - Murray

Like many of his monstrous cohorts, Murray the mummy is turned human in Hotel Transylvania 4's Monster Ray mishap. The comedic force Keegan-Michael Key voices Murray in the Hotel Transylvania 4 cast, with the former Mad Tv star also slated to voice Toad in an upcoming (and currently untitled) Super Mario movie. Key's other relevant film credits include voice work in Toy Story 4 and The Lion King's live-action remake. Since 2022, Key has taken on even more voice roles, including in the Disney version of Pinocchio, the stop-motion animated film Wendell & Wild, and the 2023 theatrical release of The Super Mario Bros. Movie​​​​​.

Brian Hull - Count Dracula

YouTube personality and impressionist Brian Hull takes over from Adam Sandler in the Hotel Transylvania 4 cast as Count Dracula, the conflicted patriarch, and perennial hotel proprietor. Hull's ability to replicate Sandler's voice was likely a key factor in this casting decision, with Dracula's tone remaining remarkably consistent despite this casting change in the latest installment in the Hotel Transylvania franchise. Hull also voiced Dracula in the animated franchise spin-off Monster Pets, proving his impressionist chops and suitability for the role in early 2021.

Fran Drescher - Eunice

The phenomenal Fran Drescher returns for her third Hotel Transylvania appearance as Eunice, wife of the oft-portrayed Frankenstein. Like Wanda before her, Eunice has enough sense to stay away from the tainted hotel water supply, leading to ample "I told you so's" for her reanimated other half. Drescher has starred in over 40 feature films to date and is currently enjoying a prominent career on Broadway, with her debut arriving in 2014's Cinderella as stepmother Madame.

Brad Abrell - Frankenstein

Of all the monsters to be turned human, Frank by far enjoys his experience the most in Hotel Transylvania: Transformania, being free of his usually cumbersome, electrified body. Frankenstein is played by prominent voice actor Brad Abrell in the Hotel Transylvania 4 cast, whose impressive vocal credits include the Men in Black franchise universe and voicing various characters in the Final Fantasy videogame series. Abrell takes over from comedy superstar Kevin James, who, alongside Sandler, stepped away from the project in 2020.

Hotel Transylvania 4 Supporting Cast & Characters

Asher Blinkoff as Dennis: The dhampir son of Johnny and Mavis, Dennis acts as the pair's motivation for renovating Hotel Transylvania. Dennis is voiced by Asher Blinkoff, whose work as a child voice actor includes Sing 2 and The Jungle Book alongside his recurring role in the Hotel Transylvania franchise.

Zoe Berri as Winnie: Dennis' friend and confidante, Winnie is the daughter of the werewolf pair Wayne and Wanda. Zoe Berri's role in Hotel Transylvania 4 is only her second accredited piece of work to date, with the young actress also playing Eliza in Live Stream.

Tyler "Ninja" Blevins as Party Monster: Better known by his online alias Ninja, Tyler Blevins is an American Twitch streamer, YouTuber, and professional gamer. 2021 marked a blistering start to Blevin's career in film, with his voice work in the Hotel Transylvania 4 cast following up a cameo appearance in the summer smash hit Free Guy.

Genndy Tartakovsky as Blobby: Blobby's transformation from a gelatinous monster into a literal restaurant-style jelly is the kind of zany humor Hotel Transylvania 4 excels at, with Blobby struggling to adjust to his new, less sentient lifestyle. Blobby is voiced in the Hotel Transylvania 4 cast by Genndy Tartakovsky in Hotel Transylvania 4, who is best known for creating various animated series on Cartoon Network, including Primal, Dexter's Laboratory, Samurai Jack, and Star Wars: Clone Wars.