The show Gossip Girl features so many notable characters, but the two most central to the story are Serena van der Woodsen and Blair Waldorf. These characters are best friends, facing ups and downs in relationships, at school, with family members, due to popularity battles, and thanks to a blogger blasting out all their secrets.

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S and B’s similar personalities, interests, and lifestyles brought them together and made them like sisters, but they do have some characteristics that are quite different. That being said, the five ways they are most alike and the five ways they are total opposites are listed below!

Alike: They Come From Affluent Families

gossip girl room

These two first met and became friends, due to the fact that their well-off parents could send them to fancy schools in New York, such as the Constance Billard School for Girls.

And even if they had not ended up in the same classes, they would have bumped into each other at the hottest and best restaurants, stores, and parties in town.

Opposite: Serena Has A Brother & An Extended Family Around, While Blair Is An Only Child

gossip girl family members

One of their differences is centered around family. Serena has a little brother, Eric, and Blair is an only child. Furthermore, Serena’s grandmother, aunt, cousin, and fake cousin all play parts in this series. For Blair, the only other relatives who pop up are her father and his partner and, later, her stepfather and his son.

Then, in the season finale, the son she has with Chuck is spotted at Serena’s wedding!

Alike: They Are Fashionistas

Blair and Serena Gossip Girl

A major similarity found in these characters is their love of fashion. Once again, their affluent lives contribute to this, since they are surrounded by the trendiest clothes and are expected to wear new and fabulous garments all the time.

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In their free time, they both enjoy shopping, and with Eleanor Waldorf being a fashion designer, Blair even ends up working in the industry.

Opposite: Serena Dresses In Boho & Glam Ways, While Blair Has Polished Signature Looks

Blair and Serena walking outside together on Gossip Girl

Though S and B are seen buying and trying on clothes together, their styles differ. When it comes to casual looks, Serena has a sort of boho vibe going on, and some of her most memorable party looks and gowns are super glam.

Blair has a preppy style and is known for signature pieces like tights and headbands. While she has worn some funkier and more glamorous pieces, there is always a level of sophistication and polish.

Alike: They’ve Always Been Drawn To One True Love

gossip girl finale

Next up is the love lives of these characters; through it all, they have both been drawn to one person (Dan for Serena/Chuck for Blair).

Sure, there have been other kisses, dates, boyfriends, and even engagements, weddings, and marriages! They always hoped they would end up with their Prince Charmings, though… and they did.

Opposite: Serena Could Go From Guy To Guy, While Blair Had Long-Term Relationships

gossip girl blair nate chuck

On a similar note, even though they both have had their fair share of romances, Serena really seems boy crazy, going from guy to guy. Blair, on the other hand, seems to be more into long-term relationships.

The way they approach their dating lives is pretty opposite.

Alike: They Can Be Total Divas

Leighton Meester as Blair and Blake Lively as Serena in Gossip Girl

There are so many positive personality traits found in these characters, but they have their moments. The Upper East Side can be a vicious place, and many times, S and B were the ring leaders.

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From ignoring their parents and physically fighting with one another to how they ruled the school on the steps of the MET, these two can both be total divas (and that is putting it nicely)!

Opposite: Serena Only Goes There When Pushed, While Blair Serves Up Attitude Immediately

Serena and Blair in Gossip Girl

To elaborate on that point, Blair can be more of a Queen B than Serena, and she lived for having her clique follow her around and do whatever she asked.

Serena is certainly capable of being nasty, but she has to really be pushed. In fact, during her worst moments of being a mean girl, she was just doing it to upset and takedown Blair.

Alike: They Are There For Their Friends When Needed Most

gossip girl wedding

A final way S and B are alike is that they are really great friends, and in true times of need, they will drop everything to help. Yes, there have been arguments and betrayals over the years, but these two, Chuck, Dan, and Nate are like a family.

Whether they were dealing with antagonists like Georgina and Ivy or whether they were dealing with personal demons and issues, they got through it… together.

Opposite: Serena Has A More Spontaneous Personality, While Blair Is A True Planner

Serena and Blair at graduation in Gossip Girl

A final way these characters are opposites has to do with their personalities. Just as Serena dresses in a more creative way and has a more bubbly attitude, she also has a more spontaneous vibe and free spirit.

And just as Blair is into polished looks and perfected details, she is a planner who must have everything just so, all the time.

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