The Big Bang Theory and Full House stars Kaley Cuoco and John Stamos attempt to sing the Full House theme song together in a new video. Cuoco is best known for playing Penny in The Big Bang Theory, which ended in 2012. The actress also starred as Cassie Bowden in the critically acclaimed HBO Max series The Flight Attendant in 2020. Stamos first rose to fame playing Blackie Parrish in General Hospital before landing his most iconic character, Jessie Katsopolis, in Full House in 1987.

While the long-running Big Bang Theory was tackling its final few seasons, Netflix revived the Full House story with a spin-off, Fuller House, in 2016. The offshoot series ran for five years with most of the original cast returning to reprise their roles. But instead of Stamos and the rest of the 1980s adult cast being front and center, a grown-up DJ (Candace Cameron Bure), Stephanie (Jodie Sweetin) and Kimmy (Andrea Barber) are put under the spotlight as they navigate parenthood while trying to maintain their personal lives. Meanwhile, the legacy cast, such as Stamos' Uncle Jesse, feature occasionally to check in on the kids and add their own life problems to the mix. Stamos also served as executive producer on Fuller House.

Related: The Big Bang Theory Season 12 Set Up A Much Better Final Season

While Cuoco never appeared in Full House, nor Stamos in The Big Bang Theory, a new clip for W Magazine shows the two actors coming together. In a video titled "Lyrical Improv," the sitcom stars try to sing the Full House theme song together, albeit with more enthusiasm on Cuoco's part. The pair also briefly attempt the Big Bang Theory theme before getting caught up in their own playful banter. Watch the full clip below.

Click here to watch the video

Aside from their singing, the pair also poke fun at each other for their respective sitcom stints. Stamos, in particular, joked about Cuoco's significant salary package from The Big Bang Theory. It's no secret that due to the show's popularity, the core cast of the CBS hit was paid around $1 million per episode. The show was so lucrative that the actress was surprised when Jim Parsons, who played Sheldon Cooper, wanted to leave The Big Bang Theory. Parsons's exit is the primary reason why the series finally wrapped after 12 years.

Looking at the clip of Cuoco and Stamos, it's clear that the actors had a lot of fun filming this small bit. In fact, they have such great rapport that it lead many users to comment that Cuoco could have played an older Michelle in Fuller House. While the rest of the core cast of Full House returned for its spin-off, the Olsen twins, Mary-Kate and Ashley (who alternated playing the role of Michelle) did not, as they've long retired from acting. Given Cuoco's resemblance to the child-stars-turned-designers and Cuoco and Stamos' fun chemistry, it isn't hard to imagine a Full House world where they could be family.

More: Big Bang Theory Already Answered Young Sheldon Season 4 Cliffhanger

Source: W Magazine