The unusual "Spider-Sense" that gives Spider-Man an edge in his crime-fighting is nothing compared to Flash's extrasensory perception. In a situation that could have gone horribly wrong, Barry Allen's own version of the classic ability saved him from an untimely end.
He may be able to do whatever a spider can, but Peter Parker's extranormal perception has always been one of the character's most useful tools. Whenever Marvel's Wall-Crawler senses danger, a familiar sensation buzzes throughout Spider-Man's body. Though he can't always tell what is happening, when his Spider-Sense starts tingling, the hero knows something's afoot. Spider-Man's amazing Spider-Sense is useful, but Peter can never be certain of what threat is causing his Spider-Sense to go off. While the power has helped Spider-Man out of a few scrapes, there's no doubt it that it needs an upgrade.
As it turns out, the hero who has made the best improvement to Spider-Sense is a speedster from the DC Universe. In Flash #4 by Francis Manapul and Brian Buccellato, the villain Mob Rule and his clones believe that they've killed Barry Allen after they shot the hero point blank while Flash used his power to see the future. In actuality, Barry is fine though he chides himself for allowing himself to be taken down so easily. As Flash regains consciousness he realizes that when he was shot, his sensory neurons were able to process information Barry wasn't even aware of. The moment the bullet made contact with Barry's skin, his body reacted before Barry could even tell that he'd been shot.
The difference between Peter Parker’s Spider-Sense and Barry Allen’s hyper perception is that Flash, or at least his senses, have a clear idea of what kind of danger he's in. This way, he can respond instantly. Spider-Man's Spider-Sense can't always tell him what's threatening him and Peter has acknowledged that his Spider-Sense is "frustratingly vague." Flash's speed powers have augmented his basic senses. Information travels so fast through Barry's noggin that he automatically responds to a stimulus before he's ever aware that he's in danger.
Now, the Spider-Sense that Peter Parker’s used for the majority of his career has obviously worked to his benefit, but it interprets far too much to ever be of practical use beyond letting Spider-Man know that something bad is going to happen. On the other hand, thanks to the Flash’s powers, he can instantaneously respond to a physical threat and react in speeds beyond real-time. His body knows exactly what's happening and how to deal with it, even if Barry isn't consciously aware of what's going on. If Peter had this form of Spider-Sense, his frustrations would be non-existent and he'd never have to worry about lethal sneak-attacks. Spider-Man may have pioneered the Spider-Sense, but the Flash has shown the potential of what that power could truly be.