Here's a rundown of every main character who dies in the Final Destination franchise. The original Final Destination started life as an X-Files spec script dubbed "Flight 180," which dealt with Scully's younger brother having a premonition that a plane he's about to board is going to crash - which is what happens when he decides not to get on it. The writer Jeffrey Reddick then reworked the idea as a movie, with X-Files duo Glen Morgan and James Wong later coming onboard to turn Final Destination into a hit movie.
The movie's clever conceit found a group of teens stalked by Death - represented as an invisible force - which plans to kill them in the order they would have died on the plane. The movie's success soon led to one of horror's most enjoyable franchises, though the fourth entry The Final Destination is usually considered the weakest of the bunch. Final Destination 6 is currently in the works, though it's unknown when it will be released.
While most horror franchises incur a high bodycount, very few feature a movie where everyone dies. The Final Destination series has had a couple of entries like this, and even if a character survives one movie they tend to get killed in the sequel. Alex (Devon Sawa), Clear (Ali Larter) and Carter (Kerr Smith) seemingly make it to the end of the original movie, only for Carter to get killed offscreen by a swinging sign in the last scene.
While the original plan for Final Destination 2 featured the return of both Clear and Alex, Sawa declined to return, so the latter was unceremoniously killed between movies by a falling brink; sadly, Clear herself is later killed in a hospital explosion. Final Destination 3 ended with Mary Elisabeth Winstead's Wendy having another gruesome premonition that the train she's on will crash and she will die alongside her sister and fellow survivor Kevin; the movie ends as they try to stop the train, but crashing sounds suggest they didn't make it.
The Final Destination ends with survivors Nick, Janet and Lori celebrating successfully cheating death - only for Nick to realize everything up to that point had really led them to that particular cafe. His realization comes a little late as a truck swerves into the building and promptly crushes the three of them to death. Final Destination 5 ends on arguably the most ironic note of the series, as survivors Sam and his girlfriend Molly board a plane to Paris to start new lives after seemingly escaping Death's design.
It turns out the movie is actually a prequel to the rest of the series, as the plane they're boarding is Flight 180 from Final Destination, and they die in the plane crash as Alex predicted. Out of the entire franchise, it appears Final Destination 2's Kimberly and Burke are the only ones to escape, and even this is debatable. The original plan for Final Destination 3 was for Winstead's Wendy to spot them on the train at the end, leading to all of them being killed, which didn't come to pass. A DVD bonus feature for Final Destination 3 dubbed "Choose Their Fate" features an alternate ending revealing Burke and Kim perished together in a freak wood chipper accident, though the canon of this is highly debatable.