Ed Helms had an extensive career in comedy before he joined The Office. Helms was a latecomer to the NBC sitcom but went on to become one of the more prominent characters throughout the long-running series. Prior to winning the role of Andy Bernard, he was a regular correspondent for The Daily Show, as well as had limited roles on Cheap Seats and Arrested Development. Joining The Office opened many doors for Helms as he began to reach a much wider audience.

While working on The Office beginning in season 3, Helms continued to appear in other projects across TV and movies. He notably worked on American Dad!Childrens Hospital, Family Guy, Funny or Die Presents, and NTSF:SD:SUV::. Helms also appeared in The Mindy Project, co-created by his co-star from The Office, Mindy Kaling. As for movies, the actor worked in a number of memorable movies following his introduction on the sitcom including titles such as Evan AlmightySemi-Pro, and Harold & Kumar Escape from Guantanamo Bay. His big break in film came with 2009's The Hangover alongside Bradley Cooper and Zach Galifianakis. Helms followed that up with a few other comedies including the sequel, The Hangover Part II, in 2011.

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In 2013, The Office came to an end but Helms showed no signs of slowing down. That same year, he appeared in We're the Millers and The Hangover Part III. Helms also starred in comedies including Vacation, Love the Coopers, The ClapperChappaquiddick, and Father Figures. The actor also kept up his presence on television with appearances in Kroll Show, Brooklyn Nine-Nine, BoJack Horseman, Running Wild with Bear Grylls, and Angie Tribeca, alongside another former co-star from The Office, Rashida Jones.

More recently, Helms appeared in the biographical comedy-drama film A Futile and Stupid Gesture in 2018. He portrayed the TV personality Tom Synder alongside a star-studded cast. Helms also served as an executive producer on the project that highlighted the rise and fall of National Lampoon. That same year, Helms played Hogan "Hoagie" Malloy in the comedy Tag, which was based on a true story. The actor starred alongside Jake Johnson, Hannibal Buress, Isla Fisher, Jon Hamm, Jeremy Renner, and once again, Rashida Jones.

The former Dunder Mifflin manager from The Office could be found in 2019's comedy, Corporate Animals. The horror-comedy made its world premiere at Sundance Film Festival in January but the film had a wider release in September. In April, Helms was revealed as the narrator for the Disney nature documentary, Penguins. Next up, Helms will appear in the comedy Coffee & Kareem. The forthcoming Netflix film directed by Michael Dowse also stars Taraji P. Henson, Betty Gilpin, King Bach, and David Alan Grier.

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