WARNING: This article contains SPOILERS for Despicable Deadpool #300
As Marvel prepares to relaunch a new Deadpool comic, they're ending the current one... by wiping Deadpool's memory. It's a big month for the Merc With a Mouth, with the highly anticipated Deadpool 2 hitting theaters as Deadpool takes over Marvel's variant covers. On top of it all, Despicable Deadpool hits its milestone Issue #300 - the final issue of the series.
For over five years, Gerry Duggan has been penning the adventures of Wade Wilson, and he certainly hasn't given the mutant an easy ride. Now, Duggan will be bowing out with a new series (titled simply Deadpool) set to hit shelves next month with Skottie Young and Nic Klein at the reins.
It's the end of an era, and to make the clear, the final issue has wiped out most of the past five years of character development for Deadpool, giving him a semi-clean slate.
Related: Deadpool Puts A Hit Out On Himself
The past few issues have seen Deadpool in a pit of self-loathing, regretting killing heroes for the evil Captain America, and letting his friends down. He went so far as to put a hit out on himself, calling down all the villains of the Marvel Universe to try and finish him off, but none succeeded. Now that the Marvel heroes have also failed to do the deed, Deadpool is taking matters into his own hands...
Despicable Deadpool #300 opens with Deadpool taking down some of the biggest heroes in the Marvel Universe (in a truly unique, and incredibly disgusting manner), before he gives up and heads off to deal with the real problem (himself)... himself. His path takes him to Bartol Utler's old lab, where he was once used for spare parts (seeing as they grow back, and all).
Once there, Wade turns to the medication on hand to not just knock him out, but wipe his memory. While Utler only used enough to wipe out a few hours at a time, Wade hooked up as many IV bags of these same chemicals as he could, effectively wiping his memory completely clean before Captain America bursts in to stop him.
The overdose may not have killed Deadpool in the traditional sense, but it's about as close as he could get, given his hyper-powerful healing factor. This also effectively reboots his history and character development throughout Duggan's run with the character, as the following panels show Deadpool inside his own mind, slaughtering his memories of everything from his time with the Avengers to his romance with Shiklah and his kiss with Rogue - even his child, Ellie.
Just to hammer the point home even further, the issue included a scene with Duggan himself, as the writer picks up Deadpool on his way to the lab... and Deadpool shoots him in the head.
Despicable Deadpool #300 ends with Wade Wilson absolved of his crimes. Well, technically deemed not mentally capable of standing trial, with the mind-wipe leaving him a drooling mess, and landing him in a care home. But it's not the end for the Merc With A Mouth; the final panel reveals that he has woken up, vaguely aware of who he is, but with most of his memory missing.
Now, it's time for a new Deadpool to rejoin the Marvel universe, without so many of those pesky feelings he's been dealing with lately. But with that same instinctive love of mayhem and chimichangas, obviously.