The Blade Trilogy was a series of films of differing levels of quality that were released in the late 90s and early 2000s that really started much of what we see in the Marvel Cinematic Universe. Wesley Snipes starred as Blade, a half-vampire, half-mortal man who protected the human race by hunting vampires. These films were all written by David S. Goyer, and all feature different directors, which probably points to the differing levels of quality in each installment. Stephen Norrington directed the first Blade, while Guillermo del Toro made Blade even cooler with a sequel that improved on the original in every way and David S. Goyer directed the worst received entry that is Blade: Trinity.
This Honest Trailer nails all of the best jokes that can be made about the Blade Trilogy. First off, this trilogy originates many of Marvel's current trademark moves, mainly by having a solid origin story, followed up by a great sequel and a horrible third film. It's also the first to feature Ryan Reynolds in a "smart ass comic book role" and the first Marvel hallway fight scene.
Secondly, they point out how many lazily named items there are in this universe. Vampires seemingly name normal, everyday objects by tacking the word "vampire" before it. Finally, we get a sense of how wild Wesley Snipes actually is. He seemed to improvise a lot of his lines with what he thought sounded good in the moment. Plus, they get a pretty solid Best in Show reference in "Starring" section by naming Parker Posey's character Danica Talos from Blade: Trinity as "Where's His Busy Bee?!"
Also, Screen Junkies points out the incorrect notion that Black Panther is the first Marvel franchise featuring a black superhero. While that may be true for what we know as the current Marvel Cinematic Universe, the Blade trilogy still counts as Marvel films. Additionally, they are all R-rated films, which dethrones Deadpool as the first R-rated superhero film. How easily we forget a mostly lackluster trilogy.
On top of the jokes about the trilogy, Screen Junkies makes a passing reference to the legendary troubled production of Blade: Trinity. Patton Oswalt, one of the A-list actors made to look ridiculous, has a fascinating and hilarious take on why it's a miracle the film was even made. Snipes was reportedly not happy with the selection of Goyer as director, and then refused to interact with anyone on set in person, resorting to sending an assistant out with sticky notes that were signed "Blade." Even worse, Goyer reportedly had to work around Snipes' absence, which resulted in stand ins and shoddy special effects. All of this resulted in Blade: Trinity, a film that would pave the way for Spider-Man 3 and X-Men: The Last Stand. After all of that, and Wesley Snipes still wants to play Blade in the MCU?
Source: Screen Junkies