Big Mouth returned to Netflix for its second season, continuing the story of a group of adolescent kids going through puberty in the grossest way possible. Co-created by long-time friends and collaborators Nick Kroll and John Mulaney, Big Mouth is inspired by the pair's pre-teen years growing up in Westchester County, New York. While the leading pair of Nick and Andrew are heavily inspired by their own lives, Big Mouth is a far more surreal and crude interpretation of one's teen years, with puberty depicted as a literal monster. Add to that talking pillows, conversing pubic hairs and the ghost of Duke Ellington and Big Mouth is definitely not adolescence as you remember it.

In season two, the boys of 5th grade navigate their tempestuous hormones as well as a new burgeoning obsession with breasts while the girls tackle body image issues, slut-shaming and boys' sudden interest in them. As the kids grow up and face the troubles of the big bad world, they take on that age old question: Can you be both horny and a decent person?

As the cast gets bigger, so does the murderer's row of comedic talents in the voice roles. To keep track of everything, here's all you need to know about Big Mouth's cast and characters in season 2.

The Main Cast - Boys

A scene from the Big Mouth Season 2 Trailer

Nick Kroll as Nick Birch/Maurice the Hormone Monster: One half of the central duo, Nick is an almost-adolescent boy who is developing at a much slower rate than his best friend, Andrew. This season, he tries to get close to the "new girl" who has developed breasts and finds himself figuring out the so-called "friend zone." He also voices Andrew’s hormone monster, a perpetually horny and foul-mouthed creature who encourages his worst instincts. Kroll, who voices an assortment of characters in the show (including Coach Steve, Lola and various ghosts), is a familiar face from film and television. Some of his most notable roles include The Douche on Parks and Recreation, Rodney from The League, and lawyer Bernie Cohen from the 2016 film Loving. His voice can he heard in Captain Underpants: The First Epic Movie, Sing, and the upcoming animated film of The Addams Family.

John Mulaney as Andrew Glouberman: Mulaney, who recently won an Emmy for his stand-up special, Kid Gorgeous, plays Andrew, the bigger of the duo who struggles to not spend every waking moment masturbating. Andrew is perpetually plagued by his hormone monster, his judgmental father, his endless neuroses, and now the addition of the Shame Wizard. Mulaney came to prominence as a writer for Saturday Night Live. Mulaney and Kroll work together frequently and have done so since their college days. The pair hosted the 2017 and 2018 Independent Spirit Awards together and appear regularly as cult hit comedy characters Gil Faizon (Kroll) and George St. Geegland (Mulaney) on shows like Comedy Bang Bang. They also had a successful Broadway run in character with The Oh, Hello Show, which is available to watch on Netflix.

Jason Mantzoukas as Jay Bilzerian: Jay is the most demented of the group and the one whose sex drive is the most polluted by toxic masculinity and desperate over-compensating. He’s obsessed with magic and sex, particularly if the latter involves pillows, although season 2 sees him questioning his sexuality (pillows are still involved). Jason Mantzoukas is another familiar face from roles on The League, Parks and Recreation and The Good Place. Podcast fans will best know him as one of the co-hosts of How Did This Get Made?

Andrew Rannells as Matthew: The token gay kid of seventh grade, Matthew delights in reporting on school gossip and providing a scathing one-liner for every occasion. Andrew Rannells is the Tony-nominated actor who rose to prominence by starring in the original Broadway production of The Book of Mormon. He also played Lena Dunham's best friend Elijah in HBO's Girls and can currently be seen in A Simple Favor.

Jordan Peele as the Ghost of Duke Ellington: For seemingly absolutely no reason, the ghost of legendary jazz musician Duke Ellington lives in Nick’s attic and occasionally offers the kids terrible advice on their daily lives. Duke makes less appearances in season 2 but does give Jordan Peele an opportunity to make a Get Out joke. Peele, the first black screenwriter to win an Oscar for Best Original Screenplay for his directorial debut (which also landed him a Best Director nomination), is currently at work on his second film, Us. He will also narrate the upcoming reboot of The Twilight Zone, for which he is also an executive producer.

Page 2: The Girls & New Characters

Maya Rudolph and Jessi Klein in Big Mouth Season 2

The Main Cast – Girls

Jessi Klein as Jessi Glaser: Jessi is a tomboy whose burgeoning puberty collides with the break-up of her parents to create immense emotional strife. In season 1, she got her first period while on a class trip and was quickly paired up with her own hormone monster. In season 2, her parents' divorce spurs her onto acting out, becoming a shoplifter and find new ways to deal with her male classmates' sudden fascination with breasts. Jessi Klein is a comedy writer who has worked on Saturday Night Live and Inside Amy Schumer, which she also appeared on.

Jenny Slate as Missy: Missy may be the most well-adjusted kid in Big Mouth: She’s smart, she has a loving relationship with her parents and friends, and a never-ending crush on Nathan Fillion (playing himself). However, her self-confidence is shaken by her own mirror image voicing every nasty thought she’s had about herself. Another SNL alum, Jenny Slate appeared with Nick Kroll on Comedy Central's Kroll Show and won critical acclaim for her part in the indie comedy Obvious Child. Her voice can be heard in The Lego Batman Movie, Zootopia, The Secret Life of Pets, and Bob's Burgers. Currently, she can be seen in Venom in the role of Dr. Dora Skirth.

Maya Rudolph as Connie the Hormone Mistress: The gender-swapped counterpoint to Maurice, Connie is the lascivious hormone monster who rules Jessi's adolescence. Where Maurice has a one track mind, Connie is more concerned with letting Jessi's emotional state run haywire, encouraging her to verbally abuse her mother and engage in casual theft. Maya Rudolph, the voice of Connie, was a Saturday Night Live cast member for seven seasons. She can currently be seen on NBC's The Good Place, playing Judge Hydrogen, and on Amazon's Forever.

June Diane Raphael as Devin: Every high school has a mean girl and Devin is the bitchiest kid in seventh grade. She delights in spreading rumors, shaming other girls and being the self-crowned queen bee. Another How Did This Get Made regular in the Big Mouth cast, June Diane Raphael plays Brianna, Jane Fonda’s daughter, on Netflix’s Grace and Frankie. She also appeared in this year's comedy Blockers and will next be in Flarsky, starring Charlize Theron and Seth Rogen.

Related: What To Expect From Big Mouth Season 3

New Characters and Cast

John Mulaney and David Thewlis in Big Mouth Season 2

Gina Rodriguez as Gena: Everyone seems to think Gena is the new girl but it’s only because she’s developed sizeable breasts and her classmates are unable to look at her in the same way again. While the boys become obsessed with objectifying her, the girls suddenly see her as an enemy, and Gena must deal with the fraught path of slut-shaming that follows. Gina Rodriguez is the Golden Globe winning star of Jane the Virgin and will soon lend her voice to the title role of Netflix's Carmen Sandiego.

David Thewlis as The Shame Wizard: While Andrew’s hormone monster encourages him to indulge in the most primal aspects of his screaming hormones, a new addition to his life seeks to ensure he suffers the consequences. Cue the Shame Wizard, a cackling spectre of guilt who stokes the worst emotions from the kids. David Thewlis voices the part. His most iconic role is arguably that of Remus Lupin in the Harry Potter movies but he's been acting in films for over 30 years, collaborating with directors like Mike Leigh (Naked), Ridley Scott (Kingdom of Heaven), and Terence Malick (The New World). He played Ares in 2017's Wonder Woman and was nominated for an Emmy for season 3 of Fargo. Thewlis is currently filming parts two and three of the Avatar series, directed by James Cameron.

John Gemberling as Tyler the Hormone Monster: After a delayed period without any signs of growth, Nick finally gets his own hormone monster. However, this one is nowhere near as experienced or scheming as Maurice. Tyler is a giddy overgrown child who doesn’t understand the rules of adolescence and sends Nick into a further spiral of bad decisions. John Gemberling is probably best known for his role as Bevers on Broad City. He writes for Comedy Central's The President Show, where he also has a recurring role as Steve Bannon, and he recently played John Belushi in the Netflix film A Futile and Stupid Gesture.

NEXT: Big Mouth Season 2 Review