Season 7 of Agents of SHIELD will include a tie-in to the Marvel Cinematic Universe. When Marvel TV and ABC launched Agents of SHIELD in 2013, the series was sold to viewers as one that would be heavily tied to the MCU. Phil Coulson was brought back from the dead after The Avengers to be the star and the first season included big connections to Captain America: The Winter Soldier. Since then, the series has also helped set up Avengers: Age of Ultron and used the Sokovia Accords from Captain America: Civil War.
However, the connectivity between Agents of SHIELD and the MCU movies started to become less frequent as the show progressed. When it did attempt to be linked to Avengers: Infinity War and Thanos, the connections didn't perfectly line up and had some questioning if Agents of SHIELD now existed in a different reality. Clark Gregg believes moving away from MCU tie-ins was for the better as it gave Agents of SHIELD more freedom with its stories. But, fans have been hopeful that the time travel adventure of season 7 will bring more MCU connections, and it sounds like that will happen.
Following the season 7 premiere of Agents of SHIELD, an interview with Maurisa Tancharoen and Jed Whedon, the show's creators, and producers Jeph Loeb and Jeffrey Bell was published by Deadline. The interview covers a variety of topics pertaining to the final season. One of the questions they were asked if Agents of SHIELD will bump into the MCU in season 7 and the creators and producers confirmed that this will be the case.
WHEDON: We’re going to bump into something.
LOEB: (LAUGHS) Yeah, we’ll bump into something.
BELL: Something will definitely happen.
The show's creative team might've stopped short of revealing how Agents of SHIELD will tie into the MCU, but the confirmation that something will happen should further increase the anticipation of fans over what it could be. The first episode of the season already brought Patton Oswalt back as another Koenig and included another familiar name from the series. It has also been confirmed that Enver Gjokaj is returning as Daniel Sousa from Agent Carter at some point, and many would like to see this lead to Hayley Atwell returning as Peggy Carter too.
Thanks to Agents of SHIELD's time travel plot for season 7, the entirety of the MCU is a possibility when discussing when and where the MCU crossover will happen. Clark Gregg has already teased that the 1950s and 1980s are two other decades that could be visited, but there's also a chance that other points in SHIELD's history will be visited. Fans should try to keep expectations in check though, as the tie-in could be minor in the grand scheme of things. But, if this "something" happens to be Agents of SHIELD dealing with The Snap or returning to the main MCU timeline, then the show's final crossover could be among its best.
Source: Deadline