Synergy bonuses can be applied by combining specific upgrades in 20 Minutes Till Dawn, and many of them have positive and negative effects that players should consider based on their playstyle. Most synergies require two upgrades to create, but arguably the best bonus needs three different upgrades to be acquired. Players can use synergies to increase their chances of surviving the full 20 minutes.

Upgrades in 20 Minutes Till Dawn can affect a variety of stats including HP, reload speed, bullet damage, elemental damage, and other aspects of a character's abilities. The best upgrades to unlock will depend on playstyle and which character is being used. There are over 60 upgrades available, but only a few synergies, so players will need to deliberately focus on obtaining these bonuses rather than trying to passively gain them. Upgrades will become available throughout the run as players kill enemies and gain XP.

Related: Vampire Survivors: How to Unlock Sir Ambrojoe

As soon as the first upgrade is available, players should consider what synergy, if any, they want to build. The possible synergies will depend on which skill tree is being worked on and what works best with the character being used in 20 Minutes Till Dawn. There are currently seven synergies that players can take advantage of. More combination perks could be added in future updates, but there has been no official announcement for additional synergies at this time.

Every Synergy Upgrade Combo In 20 Minutes Till Dawn

20 Minutes Till Dawn Synergies Guide Upgrade Combos & How They Work Gun Mastery Synergy

Synergy information can be viewed by using the Esc key to open the upgrades menu. The initial display will show any upgrades that have already been unlocked. The synergies button can be used to view details on every possible combination and the effects they have. The upgrades menu can't be opened while players are choosing a new upgrade, so planning ahead is essential to unlocking any desired synergies in 20 Minutes Till Dawn.

  • Summon Mastery (Vengeful Ghost + Dual Wield): Summon Damage +35%, Summon Attack Speed +35%, and Bullet Damage -35%
  • Mini Clip (Fan Fire + Fresh Clip): Reload Rate +100%, Bullet Damage +50%, and Max Ammo -666
  • Overload (Electro Mastery + Fire Starter): This upgrade in 20 Minutes Till Dawn causes an explosion that deals 25 damage when a burning enemy is hit with a lightning strike
  • Stand Your Ground (Siege + Fusillade): Projectiles +2, Fire Rate +25%, and Move Speed -25%
  • Frost Fire (Intense Burn + Frostbite): Inflicting freeze also inflicts burn for six damage per second
  • Death Rounds (Reaper Rounds + Light Bullets): Max HP -1, and bullets deal +10 damage
  • Gun Mastery (Armed and Ready + Power Shot + Rapid Fire): Bullet Damage +15%, Fire Rate +15%, Reload Rate +15%, Max Ammo +1, and Piercing +1

When choosing a synergy to unlock for characters in 20 Minutes Till Dawn, players will need to determine if any negative effects will outweigh the positive impact the bonuses have on their run. It's not necessary to use synergies to win a run, but doing so will add advantages that can significantly increase the chances of success, especially when using one that doesn't have any negative effects. Synergies are additional perks that players can use by combining some of the base upgrades in 20 Minutes Till Dawn.

Next: How to Unlock Toastie in Vampire Survivors

20 Minutes Till Dawn is available for PC.